His father being an itinerant minister of the Methodist Church Ghana, meant that he had to change school anytime his father was transferred, he attended the Methodist Primary Schools in Cape Coast, University Primary School, Cape Coast, Akotobinsin Methodist Primary School, Elmina, Bethany Methodist Middle School, Essikadu, Diabene Junior High School, Diabene-krom Sekondi. This continued until 1985 when he was admitted at the Mfantsipim School form two, thus completing his G. C. E Ordinary Level Examination in 1989.
On 16th January 1984, young Kwesi had a terrible accident, at 8;30pm whiles playing under moon light he fell from the top of the Methodist Manse, Essikado and landed on his back, he was confined to bed for one month and recovered quickly.
Having successfully passed his O’ Level, Rev Wilson entered Fijai Secondary School, Sekondi in 1989 to pursue Advanced Level examination completing in 1991. At Fijai, Rev Wilson was appointed Library Prefect, elected S.U. President, President of the School Choir. He was also the lead debater for the School and an active member of the drama club. This is what the then headmaster of Fijai Mr S. K. Folson said about Rev Wilson in 1991 “Wilson is a well-behaved student and there is every indication that he can go places when given the opportunity to do so. I do recommend him to any organisation where his services may be needed. He will be a great asset to that organisation”   
 After his A’ Level National Service at Assin Juaso in the Central Region of Ghana, Kwesi gained admission at the University of Cape Coast in 1992 to read Bachelor’s Degree in Educational Psychology and a Diploma in History concurrently, completing in 1997.  
After working for some time Osofo Paa Kwesi, pursued a Master of Philosophy degree in Counselling from the University of Cape Coast (2004). With the strong desire to serve the Lord, Rev. K. N. Wilson was admitted at the Trinity Theological Seminary in 2004 to pursue a Bachelor of Divinity degree and was Commissioned into the itinerant ministry at the Wesley Cathedral Sekondi in 2007. Rev. Wilson capped his academic pursuit with a Ph.D. in Counselling Psychology from the University of Education in 2015. Rev Wilson has attended several workshops locally and internationally.